Occupational and Environmental Health: Recognizing and Preventing Disease and Injury - Multiple Choice Questions - Learn & Prevent

Vinclozolin, an anti-androgen, can cause a decrease in fertility across generations in pregnant rats when exposure occurs during fetal testicular development. This is because anti-androgens disrupt the endocrine system and can interfere with the production and function of male hormones, such as testosterone. This disruption can have long-term effects on fertility and reproductive health in both male and female offspring. Option A is incorrect because an anti-androgen would actually lead to a decrease in testosterone production. Option C is incorrect because exposure to an anti-androgen during fetal testicular development would not lead to increased fertility in female offspring. Option D is incorrect because there would be a noticeable effect on fertility if the pregnant rats were exposed to an anti-androgen during fetal development.